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        基因敲除

        赛贝生物(Cellapy? )拥有丰富的基因编辑成功案例,能提供包括基因敲入、基因敲除、基因点突与修复、载体构建等全套基因编辑解决方案。

        • 服务介绍

        gRNA识别并结合在目标基因区域引导Cas9蛋白对结合位点进行切割,引起DNA双链断裂(DSB)。此时若没有外源供体DNA,通过非同源末端连接机制(NHEJ),将基因组连接起来。此时有可能导致碱基插入,丢失或者突变。


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